Vitamin D doesn’t cut back fracture danger in adults, research finds

The group discovered vitamin D3 didn’t decrease fracture danger in comparison with placebo amongst wholesome middle-aged and older adults who weren’t vitamin D poor, or had low bone mass, or osteoporosis.

“General, the outcomes from this massive medical trial don’t help the usage of vitamin D supplementation to scale back fractures in wholesome US women and men,”​ concluded lead creator Meryl LeBoff, Chief of the Calcium and Bone Division within the Division of Endocrine at Brigham and Girls’s Hospital.

“These findings don’t apply to adults with vitamin D deficiency or low bone mass or osteoporosis. ,

A lot of the individuals within the trial weren’t poor and will have reached the extent of vitamin D wanted for bone well being.,

Vitamin D dietary supplements are broadly really useful for bone well being within the basic inhabitants, however information on whether or not they forestall fractures are inconsistent.

To handle this, researchers performed a facet research to VITMIN D and Omega-3 Trial (VITAL), medical trial of greater than 25,000 adults, additionally led by Brigham.


A complete of 1,991 fractures in 1,551 individuals had been confirmed throughout a median follow-up of 5.3 years.

In contrast with placebo, supplemental vitamin D3 (2000 IU/day) didn’t cut back complete, non-vertebral or hip fractures.

The evaluation additionally confirmed that there was no impact of vitamin D3 supplementation on main osteoporotic fractures, wrist fractures, or pelvic fractures.

Results weren’t modified by baseline age, intercourse, race, physique mass index, baseline vitamin D blood degree, and private use of supplemental calcium and/or vitamin D.

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